CLINICAL SITUATION: Your patient is not tolerating or is not responding adequately to an SSRI or SNRI and the dose and duration have been adequate. Symptoms of anxiety or depression persist in spite of optimized psychosocial interventions and therapy and you believe that further psychopharmacologic intervention is required. What to do? There are four strategies … Continue reading ONCE YOU DECIDE IT IS TIME TO SWITCH ANTIDEPRESSANTS, HOW DO YOU GO ABOUT IT? 1/23/2020